Insufficient implant integration with surrounding tissues and bacterial infection are recognized as two of the major causes of biomaterials failure in clinical settings. To improve the long-term success of medical implants, recent strategies of surface functionalization are trying to simultaneously enhance host eukaryotic cell functions while inhibiting bacterial colonization. Such an integrated, multifunctional approach introduces clear advantages in comparison to classical methods of surface modification, which rarely explored a combined goal.
The aim of this symposium is thus to bring together researchers from leading groups around the world working in the development of cell instructive and antibacterial surfaces from different perspectives. Particular emphasis will be put on understanding the interaction of eukaryotic cells with bacteria at the biophysical and biomolecular level as well as on developing multifunctional surfaces via biochemical and topographical approaches.